Martin Boutelle
Robert Dickinson
robert.dickinson
@imperial.ac.uk

Department of Bioengineering
Imperial College London
London SW7 2AZ
Tel: +44 (0) 207 594 5662
Fax: +44 (0) 207 594 9817

Research Intro

Interventional Imaging and Devices

The Interventional Imaging and Devices group works on a number of projects to develop better devices that can be inserted into patients to produce improved images or information. The group is active in catheter based ultrasound and MR imaging, Radiofrequency therapy, and also works on medical information systems. The group works closely with clinical colleagues, and a recent project has been looking at how droplets disperse from patients with flu. It has also contacts with a number of small companies where some of the ideas are put into practice in actual devices.

 

Research Topics and Selected Papers

MR Interventional Imaging

Using interventional coils enables the signal-noise of MR imaging to be improved by inserting the MR coils close to the target tissue. This involves the construction of  catheter and endoscope based coils. Current work is concentrating on constructing parallel coils on an interventional platform, and a graphical user interface to aid parallel imaging has been constructed and can be downloaded for use

OMER H, DICKINSON R.   ‘A Graphical Generalized Implementation of SENSE Reconstruction using Matlab’. Concepts in Magnetic Resonance Part A Volume 36A, 3, 178-186, (June 2010) [PDF]

Ultrasound Array construction

Sub-miniature phased arrays have been built for intravascular imaging, and also at the other end of the size range for the steered delivery of high-intensity focussed ultrasound.

HAND JW, SHAW A, SADHOO N, RAJAGOPAL S, DICKINSON R J
and GAVRILOV L R  “A random phased array device for delivery of high intensity focused ultrasound”  Phys. Med. Biol. 54 (2009) 5675–5693 [PDF]

DICKINSON R.J. and KITNEY R.I., ‘Miniature ultrasonic probe construction for minimal access surgery’ Phys. Med. Biol. 49 3527-3538 (2004).

RF Electro-surgery devices

A number of electro-surgical devices are being built for tissue coagulation and ablation in collaboration with the Department of Liver Surgery, hammersmith Hospital, and Emcision Ltd. These are generally bi-polar applicators that are designed for specific applications, many of which are mounted on catheters for minimally invasive delivery.  These devices are in the process of being commercialised, and one, the Habib 4X, has shown clinical benefit in liver resection.

AYAV A., JIAO L., DICKINSON R., NICHOLLS J., MILICEVIC M.,  PELLICCI R, BACHELLIER P., HABIB N, “Liver Resection With a New Multiprobe Bipolar Radiofrequency Device” Arch Surg. 2008;143(4):396-401 [PDF] .

Respiratory Disease.

Work on respiratory disease, in collaboration with Dr A K Simonds at the Royal Brompton Hospital has included developing algorithms for the control of oxygen delivery for patients needing Long-term Oxygen therapy, and also monitoring droplet dispersion during ventilation.

Simonds AK, Hanak A, Chatwin M, Morrell MJ, Hall A, Parker KH, Siggers JH,
Dickinson RJ,   Evaluation of droplet dispersion during non-invasive ventilation, oxygen therapy, nebuliser treatment and chest physiotherapy in clinical practice: implications for management of  pandemic influenza and other airborne infections
Health Technology Assessment 2010,Vol. 14: No. 46 pp 131-1722010 [PDF]

 


 

Curriculum Vitae

DR R J DICKINSON

Robert Julian DICKINSON                                               
                                                                                               
CAREER SYNOPSIS

Degree & Doctorate in physics
20 years experience in medical electronics
15 years in Medical Devices
Board level experience in a device start-up company.
Started two companies
Project Management and departmental management experience
Technical expertise in signal processing, plus ultrasound and rf sensors
Detailed knowledge of patent applications and litigation
Experience of preparing Class II/III device technical files

           
EDUCATIONAL QUALIFICATIONS

1976

BA Hons in Physics, Class 1, Queens’ College, Cambridge University
(Pt I ;Maths, Physics, Chemistry, Crystalline State: Pt II Theoretical and Experimental Physics)

1980

PhD in Biophysics, Institute of Cancer Research, University of London
Thesis ‘Ultrasonic echo analysis in the investigation of soft tissue motion’

1994

MBA , Management School, Imperial College, London (part-time)
Dissertation ‘Trends in Hospital Information Strategy’

RECENT ACHIEVEMENTS    

  • Development of world’s smallest ultrasound array for catheter-based intra-coronary artery imaging, now marketed by Volcano Therapeutics.

  • Development of a new method of delivering Long-Term Oxygen Therapy in Chronic Obstructive Pulmonary Disease by automatically adjusting oxygen flow according to blood oxygenation. A clinical trial showed reduced hypoxia and a spin-out company won the RAE ERA Foundation Entrepreneurs Award.

  • Development of a Habib 4X electro-surgical instrument which seals blood vessels during resection of liver tumours.  Regulatory approvals were obtained via a spin-out company Emcision Ltd.  In clinical trials, blood loss was reduced >90% and mean postoperative stay halved.  >3000 units sold

PROFESSIONAL QUALIFICATIONS

I am a chartered engineer (C.Eng; Reg No.473732)). I am a member of the Institute of Physics and the Institute of Physics and Engineering in Medicine. 

PUBLICATIONS
Author of 19 granted patents, 20 scientific papers, 1 book chapter, 5 conference abstracts (details on request).  

2002 – date SENIOR LECTURER – DEPARTMENT OF BIOENGINEERING, IMPERIAL COLLEGE

Consulting and Commercial Activities:  Consultant to EMCision Ltd (www.emcision.com ), an Imperial spin-out company, and obtained a CE mark and FDA approval for their RF electro-surgery products. Founded Link-Sure Ltd (www.link-sure.com) and developed first prototype of magnetic identification interconnect. Founded Advotek Medical Devices Ltd, a medical device contract development company, including the construction of a breadboard aortic graft.

Research :  Research interests include invasive imaging, wireless sensors and medical devices. Co-investigator in EPSRC grant  ‘In-Vivo Biliary Imaging and Tissue Sampling’. Project Manager, Medical SIG, EU SIMILAR Network of Excellence. http://www3.imperial.ac.uk/people/robert.dickinson

Teaching :  Medical Imaging for MSc and final year Undergraduates. Lecturing in medical ultrasound, medical device approval, physical optics

Management and Administration : Manager and grant-holder of MagNET centre for MR device evaluation, funded by the NHS Purchasing and Supply Agency. Director of Taught Postgraduate Studies in charge of MSc project. Industry Liaison Officer Centre for Synthetic Biology.

External Activities : Member of IoP Medical Physics Group Committee. Member of Royal Academy of Engineering UK Focus for Biomedical Engineering; External Examiner - University of Aberdeen MSc

2001–2002 HEAD OF TECHNOLOGY - FLYING NULL LTD. 

A spin-out from Scientific Generics (now Sagentia) developing technologies using magnetic bar coding to provide security features for anti-counterfeiting products. I organised CE marking of the product, and tailoring to customer applications.

1990-2001  TECHNICAL DIRECTOR – JOMED IMAGING LTD (formerly Intravascular Research Ltd)

      This start-up company developed a Class III catheter based intra-coronary ultrasound scanner. The catheter has a diameter of 1mm with 64 micro-machined ultrasound elements and integrated multiplexers in a 2.9F rapid exchange delivery system, interfacing with a computer based scanner producing high quality real-time clinical images. I had overall technical control for the development project, and for meeting development milestones, including managing hardware and software projects. This involved building and managing a group of 20 engineers. I managed the preparation of the technical file and CE audit.  I assisted in raising funds, and keeping existing investors including venture capital partners informed of progress. I built up a substantial patent portfolio for the company and successfully defended a hostile action from a US competitor. The company was acquired by Jomed AG in February 2000, and has since moved its operations to a US subsidiary now owned by Volcano Therapeutics.

1985-1990         MANAGER UK RESEARCH - PICKER INTERNATIONAL LIMITED
            Design of RF coils and other MR hardware

1982-1985         MEDICAL RESEARCH COUNCIL, HAMMERSMITH HOSPITAL
            Post-doctoral research scientist, developing RF and ultrasound hyperthermia equipment

1980-1982         RESEARCH SCIENTIST - GEC HIRST RESEARCH CENTRE
            Research into image processing and image quality of ultrasound imaging.
1976-1979         PhD STUDENT  - INSTITUTE OF CANCER RESEARCH

     

Research on processing ultrasound echoes to measure their motion