We are looking for motivated researchers (PhD students and post-docs) to join in our group. Please email your CV to Dr Reiko Tanaka to ask for details.
Prospective PhD students are strongly encouraged to apply for Imperial College PhD studentship. There are also other competitive studentships. Please send your CV and research statement to Dr Reiko Tanaka.
We invite applications for an NC3R-funded PhD studentship to develop a
mathematical/computational method to design and optimise a clinically accepted
IFNγ immunotherapy for invasive fungal infection.
Invasive fungal infection usually occurs in patients under immunosuppressive treatments, such as chemotherapy for cancer, leukaemia and lymphoma and potent corticosteroid therapy. This project focuses on most common fungal infection of lung, aspergillosis, resulting in a mortality of nearly 100% if not diagnosed or treated and 30-85% even if treated. We will develop a mathematical model that can describe the regulatory mechanisms leading to progression of chronic fungal lung infection, and use the mathematical model to quantify and assess the fungicidal impact of IFNγ, determine and validate the optimal timing for administration of IFNγ, both alone and in combination with antifungal drugs, and predict optimal prophylaxis regimens for IFNγ therapy. Our in silico approach will identify most ethical and scientifically valid experiments to be conducted, replacing the initial infection experiments with computer simulation.
Applicants should have a Masters degree (or equivalent qualification) in a relevant area (computational biology, applied mathematics, control theory, or closely aligned disciplines), experiences in modelling and analysis of biological systems using differential equations and numerical methods, and strong interests in fungal biology. We look for highly motivated applicants with excellent interpersonal, written and oral communication skills and enthusiasm for exposure to a diversity of scientific projects. The PhD student will be co-supervised by Dr Reiko Tanaka and Dr Elaine BIgnell (Manchester), and the project involves close interactions with clinicians in the National Aspergillosis Centre (NAC).
A stipend and home UK/EU fees for 3 years will be awarded. The studentship is available only to UK and EU nationals. Interested applicants should first send a current CV (with the names of 2 referees) and personal statement to Dr Reiko Tanaka (firstname.lastname@example.org) by e-mail. Suitable candidates will be then asked to complete an electronic application form at Imperial College London in order for their qualifications to be addressed by College Registry.
Start date: before 1 October 2017
Applications are invited for a post of PDRA in the Department of Bioengineering at Imperial College working under the supervision of Dr Reiko Tanaka.
This post will provide an exciting opportunity to work on a project which aims to develop computational tools for a clinical decision support system that integrates and analyses clinical data to design personalised treatment strategies for atopic dermatitis, a common chronic skin disease. Our approach include application of machine learning methods to develop data-driven models, as well as control theoretical methods (model predictive control) to design optimal treatment regimens for individual patients. The project will include collaboration with experimentalists and clinicians.
Applicants should hold a PhD in a relevant area (Computational Biology, Applied Mathematics, or closely aligned disciplines) to undertake this project, experience in modelling and analysis of biological systems, expertise in modelling with differential equations and numerical methods. Applicants should also be familiar with skin biology. We look for highly motivated applicants with excellent interpersonal, written and oral communication skills and enthusiasm for exposure to a diversity of scientific projects.
This post will be based at the South Kensington Campus.