Check out the new Thesis page – with full PDFs of the 7 PhD thesis from our lab

Lab News

  • Apr 2018; Francesca and Alice’s paper on Burden-driven feedback control of gene expression is published in Nature Methods.
  • Mar 2018; George’s two papers on engineering yeast filamentous growth switching and inducible mother-specific expression are published in Communications Biology  and PLoS One.
  • Nov 2017; Charlie and Rodrigo will both be presenting at SBUK 2017 in Manchester
  • Oct 2017; Tom and Olivier will both be presenting at CRI Paris’ 10Y iGEM event
  • Aug 2017; Our latest work on burden is up on BioRxiv – exciting preprints from Olivier and Francesca


Ali Awan’s paper on engineering Baker’s yeast to produce and secrete active antibiotics is online in Nature Communications with lots of news coverage too.


This project is our pilot study to bring biosynthesis of a fungal antibiotic into yeast. Fungi naturally produce many antibiotics to keep bacteria at bay, and in the age of antimicrobial resistance (AMR) we want to use yeast synthetic biology to help out the eukaryotes in this evolutionary arms race.